✦ LIBER ✦

A unified view of the DNA-damage checkpoint

✍ Scribed by Justine Melo; David Toczyski

Book ID: 114309362
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 510 KB
Volume: 14
Category: Article
ISSN: 0955-0674
DOI: 10.1016/s0955-0674(02)00312-5

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## Abstract During mitosis, the phosphatidylinositol‐3 (PI‐3) family‐related DNA damage checkpoint kinases ATM and ATR were found on the centrosomes of human cells. ATRIP, an interaction partner of ATR, as well as Chk1 and Chk2, the downstream targets of ATR or ATM, were also localized to the centr