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A two step procedure as improved alternative to the cyclocarbonylation of allyl halides and acetylene derivatives mediated by Ni(CO)4

✍ Scribed by F. Camps; J. Coll; A. Llebaria; J.M. Moretó


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
181 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis


The addition of ally1 halides to acetylenic derivatives catalyzed by Pd(II) comnlexes. such as bis-acetonitrile oalladium(I1) bromide, followed by cvclocarbonvlation of the resultine cis adducts with Ni(CO)4 in CH3CN containine precise amounts of CH30H and Et3N is a better Fcedure than the direct cyclocarbonylation of these substrates mediated by Ni(C014 for vreoaration of cyclopentenones. speciallv for monosubstituted acetylenes or weaklv polarized disubstituted acetvlenes.