A two-step synthesis of 5-aminoisoxazole
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Martin Dines; M.L. Scheinbaum
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Article
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1969
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Elsevier Science
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French
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Synthetic approaches to 5-aminoisoxazoles have involved, for the most part, reactions of hydroxylamine with either m-substituted nitriles (2) or amidines (3) or with cyanoacetylenes (4). We wish to report a facile, high yield pathway to 3,4-disubstituted-S-aminoisoxasoles (I) comprising two syntheti