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A two-step chemical mechanism for ribosome-catalysed peptide bond formation

✍ Scribed by Hiller, David A.; Singh, Vipender; Zhong, Minghong; Strobel, Scott A.

Book ID
121849136
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
655 KB
Volume
476
Category
Article
ISSN
0028-0836

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Ribosome, the ubiquitous organelle, is the site for protein synthesis in all types of cells. The consecutive peptide bonds are formed by the transpeptidation reaction between carboxyl group of peptidyl moiety and the amino group of the aminoacyl moiety. Both the moieties are attached to the appropia