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A two-stage linkage analysis of Chinese schizophrenia pedigrees in 10 target chromosomes

✍ Scribed by Yonglan Zheng; Xiaoyan Wang; Niufan Gu; Guoyin Feng; Fanggeng Zou; Wei Qin; Jing Zhang; Wei Lin; Ran Tao; Xueqing Qian; Lin He

Book ID
116292414
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
285 KB
Volume
342
Category
Article
ISSN
0006-291X

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Autosomal linkage analysis of a Japanese
Autosomal linkage analysis of a Japanese single multiplex schizophrenia pedigree reveals two candidate loci on chromosomes 4q and 3q
✍ Naoshi Kaneko; Tatsuyuki Muratake; Hideki Kuwabara; Takanori Kurosaki; Mitsuru T πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 167 KB

## Abstract We analyzed a large multiplex schizophrenia pedigree collected in mid‐eastern Japan using 322 microsatellite markers distributed throughout the whole autosome. Under an autosomal‐dominant inheritance model, the highest pairwise LOD score (LOD = 1.69) was found at 4q (__D4S2431__: theta