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A two-part study of the aetiological role of rotavirus in lntussusception

✍ Scribed by D.L. Mulcahy; K.R. Kamath; Dr. L.M. De Silva; S. Hodges; I.W. Carter; M.J. Cloonan

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
267 KB
Volume
9
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

The aetiology of intussusception is ill‐defined, with viruses being incriminated as one of many possible aetiological agents. A two‐part study was performed by us to investigate the aetiological role of rotavirus in intussusception. Retrospective epidemiological data revealed a negative correlation between the incidence of rotaviral gastroenteritis and the incidence of intussusception. A prospective investigation employing electronmicroscopy, enzyme‐linked immunosorbent assay (ELISA), and immunofluorescence studies of faeces and fluorescent antibody studies of sera demonstrated evidence of rotavirus infection in only 2 of 24 children with intussusception. No evidence was forthcoming in this study of an aetiological role of rotavirus in intussusception.

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