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A two-generation reproductive toxicity study of the high-intensity sweetener advantame in CD rats

โœ Scribed by A. Otabe; T. Fujieda; T. Masuyama

Book ID
116463892
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
314 KB
Volume
49
Category
Article
ISSN
0278-6915

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Under Office of Prevention, Pesticides and Toxic Substances draft guidelines, CD weanling F0 rats (30 of each gender per group) inhaled tertiary amyl methyl ether vapor at 0, 250, 1500 or 3000 ppm 5 days a week and 6 h a day for 10 weeks, with vaginal cytology evaluated for weeks 8-10. The F0 animal