The presence of melanocytic naevi is the strongest known risk factor for malignant melanoma. We have developed a computer imaging system with which it is possible to make quantitative measures of the size, color, and shape of pigmented lesions. The objective of this study was to examine the genetic
A twin study of genetic and environmental contributions to gender differences in traits delineating personality disorder
✍ Scribed by Kerry L. Jang; W. John Livesley; Philip A. Vernon
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 175 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0890-2070
No coin nor oath required. For personal study only.
✦ Synopsis
The present study applied biometric genetic analyses to determine whether traits delineating personality disorders are in¯uenced by gender-speci®c genetic and environmental in¯uences. The sample consisted of 681 volunteer general population twin pairs (128 monozygotic male, 208 monozygotic female, 75 dizygotic males, 174 dizygotic females, and 96 dizygotic opposite-sex pairs). All twin pairs completed the Dimensional Assessment of Personality Pathology (DAPP-BQ) which yields 18 basic and four highorder dimensions of personality dysfunction. Heritability analyses showed that all dimensions except Submissiveness in males, and Cognitive Dysfunction, Compulsivity, Conduct Problems, Suspiciousness, and Self-harm in females were signi®cantly heritable. Sex-by-genotype analyses suggested that the genetic in¯uences underlying all but four DAPP-BQ dimensions (Stimulus Seeking, Callousness, Rejection, and Insecure Attachment) were speci®c to each gender, whereas the in¯uence of the environment was found to be the same in both genders across all dimensions. All four higher-order dimensions were also heritable across sex and in common to both genders except female dissocial personality dimensions in females, for which no heritable basis was found.
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