From procaspase-8 to caspase-8: Revisiti
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Yang Zhao; Xin Sui; Hong Ren
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Article
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2010
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John Wiley and Sons
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English
β 155 KB
## Abstract Caspaseβ8 is wellβcharacterized to initiate an apoptotic pathway triggered by the external stimuli. The proximityβdriven model recently has been proposed to interpret the activation mechanism of caspaseβ8 in soβfar unprecedent detail, in which dimerization, autocleavage, and inhibitor o