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A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

โœ Scribed by Vives, E.; Brodin, P.; Lebleu, B.


Book ID
117990108
Publisher
The American Society for Biochemistry and Molecular Biology
Year
1997
Tongue
English
Weight
639 KB
Volume
272
Category
Article
ISSN
0021-9258

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๐Ÿ“œ SIMILAR VOLUMES


A Truncated HIV-1 Tat Protein Basic Doma
โœ Vives, E.; Brodin, P.; Lebleu, B. ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› The American Society for Biochemistry and Molecula ๐ŸŒ English โš– 639 KB

Tat is an 86-amino acid protein involved in the replication of human immunodeficiency virus type 1 (HIV-1). Several studies have shown that exogenous Tat protein was able to translocate through the plasma membrane and to reach the nucleus to transactivate the viral genome. A region of the Tat protei