A trial of RIT-4237 rotavirus vaccine in 1-month-old infants

✍ Scribed by I. D. Mutz; F. Krainer; J. Deutsch; Ch. Kunz; D. E. Teuwen

• Book ID: 104775139
• Publisher: Springer
• Year: 1989
• Tongue: English
• Weight: 236 KB
• Volume: 148
• Category: Article
• ISSN: 0340-6997
• DOI: 10.1007/bf00441518

✦ Synopsis

In a double blind placebo-controlled study rotavirus vaccine RIT 4237 was offered to young infants after the fourth week of life. The vaccine was very well tolerated. Fifty-seven out of 100 vaccine recipients and 10 out of 103 placebo recipients developed rotavirus-IgM-antibodies during the 1 month follow-up period. During a 6 month follow-up, stool samples from 2 out of 12 vaccinees and from 5 out of 12 placebo recipients contained rotavirus.