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A trial of razoxane (ICRF-159) in patients with prior therapy for Modgkin's Lymphoma

✍ Scribed by Michael P. Corder; David B. McFadden; Shirley J. Bell


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
232 KB
Volume
54
Category
Article
ISSN
0008-543X

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✦ Synopsis


Razoxane (ICRF-159) was administered to 11 patients with Stage IV nodular sclerosing Hodgkin's lymphoma. A weekly schedule was employed with a starting dose of 1000 mg/m2 in divided doses. The dose was escalated up to 2000 mg/m2 weekly as tolerated. One objective partial remission was observed. The toxicity of the program was quite tolerable. Further trials of razoxane in this situation are not recommended.


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