## BACKGROUND. A Phase II study was initiated to evaluate the effectiveness of an oral regimen of etoposide and estramustine in patients with early recurrent prostate carcinoma. ## METHODS. Patients with early recurrent prostate carcinoma as indicated by an increasing prostate specific antigen
✦ LIBER ✦
A trial of razoxane (ICRF-159) in patients with prior therapy for Modgkin's Lymphoma
✍ Scribed by Michael P. Corder; David B. McFadden; Shirley J. Bell
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 232 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
Razoxane (ICRF-159) was administered to 11 patients with Stage IV nodular sclerosing Hodgkin's lymphoma. A weekly schedule was employed with a starting dose of 1000 mg/m2 in divided doses. The dose was escalated up to 2000 mg/m2 weekly as tolerated. One objective partial remission was observed. The toxicity of the program was quite tolerable. Further trials of razoxane in this situation are not recommended.
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