Background. From 1980 to 1987, 849 patients with clinically resectable rectal adenocarcinoma were randomized into a controlled clinical trial to evaluate the role of preoperative radiotherapy. Methods. Patients were given either 25 Gy during 5 to 7 days before surgery or underwent surgery alone. R
A trial of preoperative radiotherapy in the management of operable rectal cancer
β Scribed by First Report of An Mrc Working Party
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 564 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0007-1323
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There is a long and detailed history of radiation therapy as an adjuvant to surgery in operable breast cancer. The results of a large number of randomized clinical trials will be reviewed. They can be summarized by saying that although the trials show a reduction in local-regional failure with the u
## Abstract ## Background To address issues regarding the fractionation of radiotherapy (RT) and timing of surgery for rectal cancer, a multicentre trial has randomized patients to preoperative short-course RT with two different intervals to surgery, or long-course RT with delayed surgery. The pre