A trial of glucagon in the treatment of painful biliary tract disease
β Scribed by M. J. Stower; G. E. Foster; J. D. Hardcastle
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 258 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0007-1323
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β¦ Synopsis
Abstract
Seventy-one patients with a clinical diagnosis of painful biliary tract disease have been entered into a double-blind trial of glucagon. Twenty-eight were excluded as gallstones were not proved: of the remainder, 21 patients received glucagon and 22 placebo. Glucagon-treated patients were pain free 14Β·26 h(Β± 2Β·77 s.e.m.) after commencing treatment compared to 29Β·14 h(Β± 6Β·01 s.e.m.) for the placebo group (P < 0Β·05). Tenderness in the right hypochondrium showed a significant improvement when assessed at 12 h (P < 0Β·02) and 24 h (P < 0Β·1) for those given glucagon. A significant difference in blood glucose levels was seen between the two groups (P < 0Β·05). No serious side effects were observed. Glucagon relieves the pain and tenderness associated with painful biliary tract disease more effectively than conventional therapy.
π SIMILAR VOLUMES
## Abstract Ten patients with biliary-type pain, in whom investigations of the biliary tract were negative, are reported. All the patients were sexually active premenopausal women and all had evidence of infection with Chlamydia trachomatis. Five patients submitted to laparoscopy had fibrinous adhe