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A trial of glucagon in the treatment of painful biliary tract disease

✍ Scribed by M. J. Stower; G. E. Foster; J. D. Hardcastle


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
258 KB
Volume
69
Category
Article
ISSN
0007-1323

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✦ Synopsis


Abstract

Seventy-one patients with a clinical diagnosis of painful biliary tract disease have been entered into a double-blind trial of glucagon. Twenty-eight were excluded as gallstones were not proved: of the remainder, 21 patients received glucagon and 22 placebo. Glucagon-treated patients were pain free 14Β·26 h(Β± 2Β·77 s.e.m.) after commencing treatment compared to 29Β·14 h(Β± 6Β·01 s.e.m.) for the placebo group (P < 0Β·05). Tenderness in the right hypochondrium showed a significant improvement when assessed at 12 h (P < 0Β·02) and 24 h (P < 0Β·1) for those given glucagon. A significant difference in blood glucose levels was seen between the two groups (P < 0Β·05). No serious side effects were observed. Glucagon relieves the pain and tenderness associated with painful biliary tract disease more effectively than conventional therapy.


πŸ“œ SIMILAR VOLUMES


Biliary-type pain as a manifestation of
✍ J. J. Wood; J. P. Bolton; S. R. Cannon; A. Allan; B. H. O'Connor; S. Darougar πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 367 KB

## Abstract Ten patients with biliary-type pain, in whom investigations of the biliary tract were negative, are reported. All the patients were sexually active premenopausal women and all had evidence of infection with Chlamydia trachomatis. Five patients submitted to laparoscopy had fibrinous adhe