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A transgenic mouse model for TEL-JAK2-induced B-cell lymphoma/leukemia

✍ Scribed by Santos, N R dos; Ghysdael, J


Book ID
110056547
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
197 KB
Volume
20
Category
Article
ISSN
0887-6924

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## Abstract To introduce temporal control in genetic experiments targeting the endothelium, we established a mouse line expressing tamoxifen‐inducible Cre‐recombinase (Cre‐ER^T2^) under the regulation of the vascular endothelial cadherin promoter (VECad). Specificity and efficiency of Cre activity