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A Transcriptional Logic for Nuclear Reprogramming

โœ Scribed by Kit T. Rodolfa; Kevin Eggan

Book ID
116353222
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
415 KB
Volume
126
Category
Article
ISSN
0092-8674

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## Abstract Ectopic expression of a defined set of transcription factors chosen from Oct3/4, Sox2, cโ€Myc, Klf4, Nanog, and Lin28 can directly reprogram somatic cells to pluripotency. These reprogrammed cells are referred to as induced pluripotent stem cells (iPSCs). To date, iPSCs have been success