A transbasisphenoidal approach for selective occlusion of the middle cerebral artery in rats
β Scribed by V. Albanese; C. Tommasino; A. Spadaro; F. Tomasello
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 840 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1420-682X
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## Abstract Mitochondrial dysfunction has been proved to contribute to ischemiaβinduced brain damage. In this study, which used a rat middle cerebral artery occlusion (MCAO) model, the protective effects of huperzine A (HupA) against mitochondrial dysfunction and brain damage were investigated. MCA
This study examined the effects of two stabilised analogues of TRH, RX 77368 and CG 3509, in a rat cerebral ischaemia model produced by unilateral occlusion of the middle cerebral artery. The analogues were given intraventricularly after artery occlusion. The extent of the cortical ischaemia was eva