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A Total Synthesis of the Epoxyquinone Based Antifungal Natural Product (.+-.)-Ambuic Acid.

✍ Scribed by Goverdhan Mehta; Subhas Chandra Pan

Publisher
John Wiley and Sons
Year
2005
Weight
10 KB
Volume
36
Category
Article
ISSN
0931-7597

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✍ Jamesβ€…A. Bull; Emilyβ€…P. Balskus; Richardβ€…A.β€…J. Horan; Martin Langner; Stevenβ€…V. πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 479 KB

## Abstract The bengazoles are a family of marine natural products that display potent antifungal activity and a unique structure, containing two oxazole rings flanking a single carbon atom. Total syntheses of bengazole A and B are described, which contain a sensitive stereogenic centre at this pos