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A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells

✍ Scribed by Downes, C. Stephen; Clarke, Duncan J.; Mullinger, Ann M.; Giménez-Abián, Juan F.; Creighton, Andrew M.; Johnson, Robert T.


Book ID
109790499
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
533 KB
Volume
372
Category
Article
ISSN
0028-0836

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## Abstract **Background:** Various mitotic events are controlled by Cdc2‐cyclin B and other mitotic kinases. Aurora/Ipl1‐related mitotic kinases were proved to play key roles in mitotic progression in diverse lower organisms. Aurora‐A is a mammalian counterpart of aurora/Ipl1‐related kinases and i