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A three-step strategy of induction chemotherapy then chemoradiation followed by surgery in patients with potentially resectable carcinoma of the esophagus or gastroesophageal junction

✍ Scribed by Jaffer A. Ajani; Ritsuko Komaki; Joe B. Putnam; Garrett Walsh; Jon Nesbitt; Peter W. Pisters; Patrick M. Lynch; Ara Vaporciyan; Roy Smythe; Sandeep Lahoti; Issac Raijman; Stephen Swisher; Faye D. Martin; Jack A. Roth

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
92 KB
Volume
92
Category
Article
ISSN
0008-543X

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✦ Synopsis

BACKGROUND.

Patients with locoregional carcinoma of the esophagus or gastroesophageal junction have a poor survival rate after surgery. Preoperative chemotherapy or chemoradiotherapy has not improved the outcome for these patients.

Our study was designed to assess the feasibility of preoperative induction combination chemotherapy in addition to chemoradiotherapy to improve the curative resection rate, local control, and survival.

📜 SIMILAR VOLUMES

Preoperative induction of CPT-11 and cis
Preoperative induction of CPT-11 and cisplatin chemotherapy followed by chemoradiotherapy in patients with locoregional carcinoma of the esophagus or gastroesophageal junction
✍ Jaffer A. Ajani; Garrett Walsh; Ritsuko Komaki; Jeff Morris; Stephen G. Swisher; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 96 KB

## Abstract ## BACKGROUND Patients with localized esophageal carcinoma often develop locoregional and distant disease recurrence. The current study investigated the outcome of a new chemotherapy combination as induction therapy before chemoradiotherapy. ## METHODS Forty‐three patients with resec