## Abstract The synthesis of a model water‐soluble drug carrier system based on poly(ethylene glycol) (PEG) block copolymers is described. In the system, two blocks of PEG are connected via a biodegradable oligopeptide or amino acid linkage incorporating at least one glutamic acid residue. A drug m
A thermosensitive hydrogel based on biodegradable amphiphilic poly(ethylene glycol)–polycaprolactone–poly(ethylene glycol) block copolymers
✍ Scribed by Gong, ChangYang; Qian, ZhiYong; Liu, CaiBing; Huang, MeiJuan; Gu, YingChun; Wen, YanJun; Kan, Bing; Wang, Ke; Dai, Mei; Li, XingYi; Gou, MaLing; Tu, MingJing; Wei, YuQuan
- Book ID
- 120328350
- Publisher
- Institute of Physics
- Year
- 2007
- Tongue
- English
- Weight
- 644 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0964-1726
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Poly(ethylene glycol)-poly(L-lactide) diblock and triblock copolymers were prepared by ring-opening polymerization of L-lactide with poly(ethylene glycol) methyl ether or with poly(ethylene glycol) in the presence of stannous octoate. Molecular weight, thermal properties, and crystalline structure o
The biodegration behavior of polycaprolactone-poly(ethylene glycol) block copolymer (PCL-b-PEG) was identified by degradation tests in vitro and in vivo. The tests in vitro and in vivo were carried out by immersing samples in pH 5.0, 7.2 and 9.0 buffer solutions with or without lipase at 25.0, 37.0