A Therapeutic Vaccine Approach to Stimulate Axon Regeneration in the Adult Mammalian Spinal Cord
β Scribed by D.W Huang; L McKerracher; P.E Braun; S David
- Book ID
- 117607587
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 274 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0896-6273
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Central nervous system axons regenerate into a Schwann cell implant placed in the transected thoracic spinal cord of an adult rat. The present study was designed to test whether these regenerated axons are capable of conducting action potentials. Following the transection and removal of
Insulin-like growth factor-I (IGF-I) promotes axonal regeneration in the peripheral nervous system and this effect is enhanced by platelet-derived growth factor (PDGF). We decided, therefore, to study the effects of these factors on axonal regeneration in the adult rat spinal cord. Semipermeable pol