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A theoretical approach to the estimation of tissue flows using tritiated water as indicator

✍ Scribed by A. Sánchez Navarro

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
545 KB
Volume
84
Category
Article
ISSN
0022-3549

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✦ Synopsis

An alternative method for the determination of flow rates to individual organs or tissues that collectively comprises experimental isolated preparations is described. The isolated hindlimb constitutes a good example of such an experimental preparation. After injecting a bolus dose of tritiated water to the arterial side, the amount of marker (tritiated water) remaining in different tissues at various time is determined. From these experimental data, the regional flow rate to individual tissues can be estimated, applying either a physiological model approach or statistical moment theory.

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