A TH1→TH2 switch is a critical step in the etiology of HIV infection
✍ Scribed by Mario Clerici; Gene M. Shearer
- Book ID
- 103583993
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 704 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
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CD30 is a member of the tumour necrosis factor/nerve growth factor receptor superfamily, which is expressed on CD4+ and CD8+ T-cell clones which produce T helper (Th) 2-type cytokines. It has been proposed that disease progression in HIV-1 is associated with Th1 to Th2 cytokine switching. In 70 cuta
## Abstract The Th1–Th2 balance plays a pivotal role in determining the outcome of an immune response to an infectious organism. It is proposed that during HIV infection, disease progression is characterized by a loss of Th1 activity, a shift to a more ‘allergic’ Th2‐type response and hence loss of