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A test of proposed rules for helix capping: Implications for protein design

✍ Scribed by Martin Sagermann; Lars-Göran Mårtensson; Walter A. Baase; Brian W. Matthews


Book ID
111753379
Publisher
Cold Spring Harbor Laboratory Press
Year
2009
Tongue
English
Weight
191 KB
Volume
11
Category
Article
ISSN
0961-8368

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## Abstract __In our search for a catalyst for the transamination reaction of aspartic acid to form oxaloacetate, twenty‐five forty‐two‐residue sequences were designed to fold into helix‐loop‐helix dimers and form binding sites for the key intermediate along the reaction pathway, the aldimine. This