A tentative mechanism of the ternary complex formation between phosphorylase kinase, glycogen phosphorylase b and glycogen
β Scribed by Iraida E. Andreeva; Valentina F. Makeeva; Boris I. Kurganov; Nataliya A. Chebotareva; Nataliya B. Livanova
- Book ID
- 117110456
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 279 KB
- Volume
- 445
- Category
- Article
- ISSN
- 0014-5793
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## Abstract Selfβassociation of phosphorylase kinase (PhK) and its interaction with glycogen (__M__=5500βkDa) and phosphorylase __b__ (Ph__b__) has been studied using analytical ultracentrifugation and turbidimetry under the conditions of molecular crowding arising from the presence of high concent
The glucose-induced switch between glycogen phosphorylase and glycogen synthase in the liver is investigated by means of a theoretical approach based on a minimal, bicyclic cascade model involving the reversible phosphorylation of the two enzymes. The aim of the analysis is to evaluate the contribut