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A temperature sensitive nonsense mutation affecting the synthesis of a major protein of Escherichia coli K12

โœ Scribed by Cooper, Stephen ;Ruettinger, Therese

Publisher
Springer
Year
1975
Tongue
English
Weight
551 KB
Volume
139
Category
Article
ISSN
0026-8925

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โœฆ Synopsis

A temperature sensitive nonsense (TSN) mutant of E. coli K12 has been isolated in which a major bacterial protein is not synthesized at 42 degrees C. This protein is found in the parental strain at 42 degrees C and in cells rendered temperature resistant due to the insertion of a number of different nonsense suppressors or the normal allele of the mutant locus.

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