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A temperature-sensitive mutant isolated from mouse FM3A cells defective in DNA replication at a non-permissive temperature

โœ Scribed by Masao Hyodo; Kenshi Suzuki

Book ID
115891487
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
933 KB
Volume
137
Category
Article
ISSN
0014-4827

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DNA replication and transcription in a temperature-sensitive mutant of E. coli with a defective DNA gyrase B subunit
โœ Mirkin, S. M. ;Shmerling, Zh. G. ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer ๐ŸŒ English โš– 532 KB

A temperature-sensitive mutant of E. coli with a defective DNA gyrase B subunit has been obtained. The mutation is expressed in the thermolability of DNA gyrase in vitro and in DNA relaxation in vivo. DNA replication in the mutant does not stop under non-permissive conditions; its rate gradually fal