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A teleost in vitro reporter gene assay to screen for agonists of the peroxisome proliferator-activated receptors

✍ Scribed by Gele Liu; Thomas W. Moon; Chris D. Metcalfe; Lucy E. J. Lee; Vance L. Trudeau


Book ID
111847853
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
158 KB
Volume
24
Category
Article
ISSN
0730-7268

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The peroxisome proliferator-activated receptors (PPARs) are nuclear receptors activated by fatty acids and their metabolites. The PPAR␦ subtype is believed to be involved in lipoprotein regulation and may have a role in reverse cholesterol transport. While the range of biological roles of PPAR␦ stil