A technique for marking the mucosa of the gastrointestinal tract after polypectomy

✍ Scribed by J. P. Sauntry; K. P. Knudtson

• Publisher: John Wiley and Sons
• Year: 1958
• Tongue: English
• Weight: 397 KB
• Volume: 11
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(195805/06)11:3<607::aid-cncr2820110322>3.0.co;2-y

✦ Synopsis

HE DESIRABILITY of having some way to T mark the m u m a of the gastrointestinal tract has no doubt occurred to many. The removal of a rectal polyp and the subsequent report by the pathologist of malignant change not infrequently gives rise to an unsuccessful search for the site of excision. However, the 10 days to 2 weeks between removal and the pathology report are sufficient for healing to take place, and the exact site of the excision can no longer be found. Although there may be other uses for the technique to be described, it was this specific problem that spurred us to attempt to devise a suitable method for marking the mucous membrane of the gastrointestinal tract.

In our search for a suitable dye, two factors were of paramount importance: (I), that the dye be of large particle size to ensure maintenance of the dye in the injected area with only minimal lymphatic spread; and (2), that the dye be well tolerated by the tissues locally and, if absorbed, be nontoxic to other tissues in the body.