A Targeted Approach to a Giant Gastrointestinal Stromal Tumor of the Esophagus
โ Scribed by Arvind Krishnamurthy
- Book ID
- 120715067
- Publisher
- Springer-Verlag
- Year
- 2013
- Tongue
- English
- Weight
- 436 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0975-7651
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract. These tumors span a wide clinical spectrum from benign to malignant and have long been recognized for their nearly absolute resistance to chemotherapy and radiation treatment. We revie
As a result of major recent advances in understanding the biology of gastrointestinal stromal tumors (GISTs), specifically recognition of the central role of activating KIT mutations and associated KIT protein expression in these lesions, and the development of novel and effective therapy for GISTs