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A Taq I polymorphism at the bovine locus for uridine monophosphate synthase (UMPS)

✍ Scribed by B. SCHWENGER; S. SCHÖBER; D. SIMON


Book ID
114705806
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
56 KB
Volume
23
Category
Article
ISSN
0268-9146

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Uridine monophosphate synthase (UMPS) catalyzes the final two steps of de novo pyrimidine synthesis, converting orotic acid to uridine 5' monophosphate. In Holstein and Red Holstein cattle, deficiency of UMPS (DUMPS) is inherited as a monogenic autosomal recessive trait. Heterozygous animals are phe