A systematic synthetic approach to phosphinophenyl-glycine and -alanine chiral phosphine ligands with amino acid moieties

✍ Scribed by Michael Tepper; Othmar Stelzer; Thomas Häusler; William S. Sheldrick

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 164 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)00335-3

✦ Synopsis

or~bo-and pnra-phosphinophenyl derivatives of glycine and alanine have been synthesised by nucleophilic phosphination of Z-and 4-fluorophenylglycine and -alanine with Ph(R)PK (R = Me, Ph) The structure of 2-diphenylphosphino-a-phenylglycine has been identified by X-ray analysis