𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A systematic review of FOLFOXIRI chemotherapy for the first-line treatment of metastatic colorectal cancer: improved efficacy at the cost of increased toxicity

✍ Scribed by F. Montagnani; A. Chiriatti; G. Turrisi; G. Francini; G. Fiorentini

Book ID
109043706
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
147 KB
Volume
13
Category
Article
ISSN
1462-8910

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Increased toxicity and lack of efficacy
Increased toxicity and lack of efficacy of Rofecoxib in combination with chemotherapy for treatment of metastatic colorectal cancer: A phase II study
✍ Carlos R. Becerra; Eugene P. Frenkel; Raheela Ashfaq; Richard B. Gaynor πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 207 KB πŸ‘ 1 views

## Abstract Preclinical and clinical models have demonstrated that cyclooxygenase‐2 (COX‐2) is overexpressed in primary and metastatic colorectal tumors. In preclinical models, there appears to be additive or synergistic effects when combining 5‐Fluorouracil (5‐FU) with nonsteroidal anti‐inflammato