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A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

โœ Scribed by Brummelkamp, T. R.

Book ID
118049202
Publisher
American Association for the Advancement of Science
Year
2002
Tongue
English
Weight
361 KB
Volume
296
Category
Article
ISSN
0036-8075

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โœ Ajamete Kaykas; Randall T Moon ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› BioMed Central ๐ŸŒ English โš– 402 KB

Background: RNA interference (RNAi) is an evolutionarily conserved process that functions to inhibit gene expression. The use of RNAi in mammals as a tool to study gene function has rapidly developed in the last couple of years since the discovery that the function-inhibiting units of RNAi are short