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A System for Low Field Imaging of Laser-Polarized Noble Gas

✍ Scribed by G.P. Wong; C.H. Tseng; V.R. Pomeroy; R.W. Mair; D.P. Hinton; D. Hoffmann; R.E. Stoner; F.W. Hersman; D.G. Cory; R.L. Walsworth

Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
259 KB
Volume
141
Category
Article
ISSN
1090-7807

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✦ Synopsis

We describe a device for performing MRI with laser-polarized noble gas at low magnetic fields (<50 G). The system is robust, portable, inexpensive, and provides gas-phase imaging resolution comparable to that of high field clinical instruments. At 20.6 G, we have imaged laser-polarized 3 He (Larmor frequency of 67 kHz) in both sealed glass cells and excised rat lungs, using Ο³0.1 G/cm gradients to achieve Ο³1 mm 2 resolution. In addition, we measured 3 He T* 2 times greater than 100 ms in excised rat lungs, which is roughly 20 times longer than typical values observed at high (Ο³2 T) fields. We include a discussion of the practical considerations for working at low magnetic fields and conclude with evidence of radiation damping in this system.

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