A synthetic solution to gene delivery
โ Scribed by Doerr, Allison
- Book ID
- 109936646
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 137 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1552-4450
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๐ SIMILAR VOLUMES
## Background: Efficient and non-toxic gene delivery, preferably with non-viral dna vectors readily transferable to clinical practice, is generally regarded as a major limitation for gene therapy. ## Methods: A 31 amino acid, integrin-targeted bifunctional synthetic peptide (polylysine-molossin),
## Abstract Synthetic nonionic surfactant vesicles (niosomes) are a colloidal system with closed bilayer structures, displaying distinct advantages in stability and cost compared with liposomes. In this article, polysorbate cationic niosomes (PCNs) were developed as gene carriers. The PCNs comprise