A Synthetic Route to a Novel Type of Conformationally Constrained N-Aryloxazolidinones.
โ Scribed by Rosa Griera; Carme Cantos-Llopart; Mercedes Amat; Joan Bosch; Juan-C. del Castillo; Joan Huguet
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 26 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Multi-membered O,N,S-heterocycles R 0692
A Synthetic Route to a Novel Type of Conformationally Constrained N-Aryloxazolidinones. -Compound (X) is synthesized as a key intermediate for various oxazolidinones like compound (XII), which is tested for its antibacterial activity. -
๐ SIMILAR VOLUMES
Dialkyl and dithioalkyl N-protected 1-aminoalkylphosphonates were synthesized using reactions of benzyl carbamate, aldehydes and chlorophosphites, or dithioalkyl chlorophosphite, respectively. This represents a novel synthetic method for 1aminoalkylphosphonates.
A novel thia-Fries rearrangement of sulfamates 1 in AlCl 3 giving good yields of para-2 and ortho-3 arylhydroxysulfonamides offers a new and efficient route to these sulfonamides.