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A synthetic peptide analog of the putative substrate-binding motif activates protein kinase C

✍ Scribed by Colin House; Phillip J. Robinson; Bruce E. Kemp

Book ID
115921853
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
437 KB
Volume
249
Category
Article
ISSN
0014-5793

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Use of the Synthetic Peptide Neurogranin
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✍ A. Gonzalez; E. Klann; J.S. Sessoms; S.J. Chen πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 518 KB

The synthetic peptide neurogranin \({ }_{(28-43)}\), the sequence of which is homologous to the phosphorylation site of the brain specific protein kinase \(C\) (PKC) substrates neurogranin and neuromodulin, was tested for its utility as a PKC substrate in crude tissue homogenates. The phosphorylatio