✦ LIBER ✦

A synthetic approach to the mitosenes

✍ Scribed by J. Rebek Jr.; J.-C.E. fsGehret

Publisher: Elsevier Science
Year: 1977
Tongue: French
Weight: 114 KB
Volume: 18
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)83146-4

No coin nor oath required. For personal study only.

✦ Synopsis

Mitosenes, the chemical degradation products of the mitomycins, 1 are synthetically accessible through a number of approaches which build the pyrrolisidine system onto an existing 6membered ring.

2 We offer here an alternative, rapid assembly of the ring system, from which access to optically active mitosenes appears feasible. Our approach is based on Huisgen's 394 pyrrole synthesis formalized below; applied to the case at hand, a mUnchnone is generated from

📜 SIMILAR VOLUMES

A mercury mediated route to the mitosene

A mercury mediated route to the mitosenes

✍ Samuel Danishefsky; John Regan 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 172 KB

## FFfm A Mitsunobu type of coupling is used to prepare a complex phenyl a y ether which undergoes a Claisen rearrangement. A synthetic route to a mitosene is achieved.

A synthetic approach to the plakortones

✍ Christian Bittner; Andrea Burgo; Patrick J. Murphy; Chi.H. Sung; Andrew J. Thorn 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 127 KB

Synthetic Approach to Malibatol A.

✍ George A. Kraus; Ikyon Kim 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 70 KB 👁 2 views

A synthetic approach to fomannosin

✍ Katsuji Miyano; Yasufumi Ohfune; Shizuo Azuma; Takeshi Matsumoto 📂 Article 📅 1974 🏛 Elsevier Science 🌐 French ⚖ 185 KB

A synthetic approach to Portulal

✍ T. Tokoroyama; K. Matsuo; R. Kanazawa; H. Kotsuki; T. Kubota 📂 Article 📅 1974 🏛 Elsevier Science 🌐 French ⚖ 208 KB

Synthetic Approaches to Phomactin A

✍ Kevin P. Cole; Richard P. Hsung 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 47 KB 👁 1 views