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A Synthesis of Trisubstituted Alkenes by a Ru-Catalyzed Addition.

✍ Scribed by Barry M. Trost; Hong C. Shen; Anthony B. Pinkerton

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
33
Category
Article
ISSN
0931-7597

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The enamide group is an important substructure that is often found in natural products [1] and synthetic drugs that have, amongst others, sedative, [2] cytotoxic, [3] or anti-inflammatory [4] properties. Moreover, they are versatile synthetic intermediates that can serve as substrates for polymeriza