A synthesis of enol lactones

✍ Scribed by A.P. Gara; R.A. Massy-Westropp; G.D. Reynolds

• Book ID: 104239971
• Publisher: Elsevier Science
• Year: 1969
• Tongue: French
• Weight: 113 KB
• Volume: 10
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)88645-7

✦ Synopsis

This investigation began in an attempt to develop an efficient new synthetic method for the stereospecific synthesis of the Y-alkylidena double bond in the sesquiterpene, freelingyne, I (1). Although methods are avsilable for the preparation of enol la&ones they usually lack stereochemical control.

Enol la&ones can be prepared by using the Wittig reaction between stable phosphorus ylids (II, B I alkyl or alkoxyl) CH