Infection with high-risk human papillomaviruses (HPV), is the most significant risk factor for cervical cancer and it may be possible to prevent this malignancy by immunisation. Before immunisation programmes can be designed, however, it is necessary to know the age of acquisition and all routes of
A survey of seroprevalence of human papillomavirus types 16, 18 and 33 among children
โ Scribed by Veronika af Geijersstam; Carina Eklund; Zhaohui Wang; Martin Sapp; John T. Schiller; Joakim Dillner; Lena Dillner
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- French
- Weight
- 72 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0020-7136
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โฆ Synopsis
The importance and natural history of HPV infections in childhood is incompletely understood. We performed a survey for presence of serum antibodies to HPV capsids among 1031 children aged 0 to 13 years, resident in Stockholm, Sweden. The HPV seroprevalence among these children was 3.0% for HPV16, 0.6% for HPV18 and 2.7% for HPV33. By comparison, among simultaneously analyzed positive control panels comprising women with CIN or healthy women with type-specific cervical HPV DNA, seroprevalence of HPV 16, 18 and 33 was 69%, 58% and 63% respectively. The results suggest that HPV infection in childhood is not common.
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