A surprising rearrangement of a carbeneethylene sulfide ylide
✍ Scribed by Eunju Lee Tae; Zhendong Zhu; Matthew S Platz
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 263 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Efficient synthesis of benzofuroquinolizine ketone 1 was accomplished in four steps from ethyl 3benzofuranacetate. The O-analogue of the Pictet-Spengler cyclization was used to form the benzofuroquinolizine ring structure as a key step.
📜 SIMILAR VOLUMES
We would like to report the observation of nuclear spin polarization in 1,2-diphenylethyl phenyl sulfide (I) formed by action of benzyne on dibenzyl sulfide (II). When a solution of 1-(2-carboxyphenyl)-3,3-dimethyltetrazene
Acetylene (3) is formed by the novel reaction of a foiled carbene (6). We have described the efficient (ca. 80% yield) conversion of (1; X = Br or H) into ( ) and ( ) (ratio 4.2:1) upon treatment with "BuLi.' Two mechanisms can be envisaged for the formation of the