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A superoxide anion generator, pyrogallol induces apoptosis in As4.1 cells through the depletion of intracellular GSH content

โœ Scribed by Woo Hyun Park; Yong Whan Han; Suhn Hee Kim; Sung Zoo Kim


Book ID
113809007
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
519 KB
Volume
619
Category
Article
ISSN
0027-5107

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A superoxide anion generator, pyrogallol
โœ Sang WooK Kim; Yong Whan Han; Soo Teik Lee; Hey Jin Jeong; Seong Hun Kim; In Hee ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 647 KB

## Abstract We investigated the in vitro effects of pyrogallol on cell growth, cell cycle regulation, and apoptosis in HeLa cells. Pyrogallol inhibited the growth of HeLa cells with an IC~50~ of approximately 45 ยตM. Pyrogallol induced arrest during all phases of the cell cycle and also very efficie