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A sulindac analogue is effective against malignant pleural effusion in mice

โœ Scribed by Moschos, Charalampos; Psallidas, Ioannis; Cottin, Thomas; Kollintza, Androniki; Papiris, Spyros; Roussos, Charis; Stathopoulos, Georgios T.; Giannis, Athanassios; Kalomenidis, Ioannis

Book ID
119320515
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
376 KB
Volume
73
Category
Article
ISSN
0169-5002

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Sulindac, a non-steroidal anti-inflammatory drug, has been reported to lead to tumour regression in cases of human polyposis coli. We have investigated the effects of this drug on the growth of 1,2-dimethylhydrazine (DMH)-induced mouse colonic tumours. In one experiment, DMH and oral sulindac were a