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A Sulfoxide Version of the Julia–Lythgoe Olefination: A New Method for the Synthesis of Olefins from Carbonyl Compounds and Sulfoxides with Carbon–Carbon Coupling

✍ Scribed by Tsuyoshi Satoh; Noriko Hanaki; Noriko Yamada; Tohru Asano


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
187 KB
Volume
56
Category
Article
ISSN
0040-4020

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Ligand exchange reaction of I~-mesyloxy sulfoxides or 13-acetoxy sulfoxides, which were derived from alkenyl aryl sulfoxides and aldehydes in two steps, with n-BuLi or EtMgBr at low temperature gave allenes in good yields. Optically active allenes were synthesized starting from optically active 2-ph