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A study on the relationship between breast cancer molecular classification and prognosis

โœ Scribed by X.S. Chen; K.W. Shen; W.T. Yang; H.F. Lu; J. Wu; J.S. Lu; Z.M. Shao; Z.Z. Shen


Book ID
119598263
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
58 KB
Volume
6
Category
Article
ISSN
1359-6349

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The prognostic significance of p53 gene abnormalities was investigated in 9 I9 primary breast-cancer patients. p53 expression and tumour-cell proliferation fraction determined by MIB-I count, p53 exon 5 and 6 mutations and HER-Z/neu oncogene amplification were detected by immunohistochemistry, PCR-S