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A study on the open chain model for transition state structures in the nucleophilic addition to β-substituted carbonyl compounds and its application to the 1,3 asymmetric induction

✍ Scribed by Carlo Bonini; Vittorio Esposito; Maurizio D'Auria; Giuliana Righi


Book ID
108378741
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
314 KB
Volume
53
Category
Article
ISSN
0040-4020

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Summarv : The transition state structures for addition of LiH to 1, 2, and 3 are computed and analyzed at MP2/6-3lG(d)//HF/6\_3lG(d). Three factors are found to be important for the relative energies of the transition state structures: (i) the conformational energy of the aldehyde; (ii) the interac