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A study on the degradation efficiency and mechanisms of ethyl violet by HPLC–PDA–ESI–MS and GC–MS

✍ Scribed by Wenlian-William Lee; Wen-Hsin Chung; Chung-Shin Lu; Wan-Yu Lin; Chiing-Chang Chen


Book ID
119367086
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
978 KB
Volume
98
Category
Article
ISSN
1383-5866

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## Abstract Degradation products obtained under severe alkaline stress of the drug substance ENA 713, a compound developed for the treatment of DAT (dementia of the __Alzheimer__ type), have been identified by on‐line coupled reversed phase HPLC‐GC‐MS as 3‐hydroxyaceto‐phenone and 3‐hydroxystyrene.